Bilastine vs. hydroxyzine: occupation of brain histamine H 1 ‐receptors evaluated by positron emission tomography in healthy volunteers
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منابع مشابه
Bilastine vs. hydroxyzine: occupation of brain histamine H1-receptors evaluated by positron emission tomography in healthy volunteers
AIM A close correlation exists between positron emission tomography (PET)-determined histamine H1 -receptor occupancy (H1 RO) and the incidence of sedation. Antihistamines with H1 RO <20% are classified as non-sedating. The objective was to compare the H1 RO of bilastine, a second generation antihistamine, with that of hydroxyzine. METHODS This randomized, double-blind, crossover study used P...
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ژورنال
عنوان ژورنال: British Journal of Clinical Pharmacology
سال: 2014
ISSN: 0306-5251,1365-2125
DOI: 10.1111/bcp.12421